Special Issue: Discrete dynamical modeling of biological systems
Dr. Claus Kadelka, Dr. Réka Albert, and Dr. Laurence Calzone are calling for papers to their special issue on Discrete dynamical modeling of biological systems. Deadline for manuscript submissions is 19 May 2026.
Understanding how complex biological behaviors emerge from interacting molecular, cellular, or ecological components remains a central challenge in systems biology. Discrete dynamical models — including Boolean networks, cellular automata, Petri nets, and agent-based approaches — provide powerful tools to investigate such systems, especially when detailed kinetic data are scarce or system states are inherently discrete. Discrete models have proven valuable in exploring gene regulatory networks, cell fate decisions, tissue patterning, and population-level dynamics.
This collection invites submissions that advance the theory, application, or integration of discrete modeling frameworks to study biological phenomena across scales—from intracellular regulation to multi-species ecosystems. We welcome methodological contributions that develop new algorithms or theoretical insights, as well as applied studies that leverage discrete models to interpret experimental data or generate testable predictions. Of particular interest are hybrid models combining discrete and continuous dynamics, data-informed model selection and analysis, and studies bridging discrete models with omics or imaging datasets. By gathering a diverse set of contributions, this collection aims to highlight the growing relevance and versatility of discrete dynamical modeling in uncovering the dynamic functioning and behaviors of living systems.
Submission deadline: 19 November 2026
Source and more information: https://www.nature.com/collections/jfibbffaje
